the impact of drugs for brain


CHAPTER I
INTRODUCTION
1.1  Background of the problem
           Medicine is not strange word for us especially for the people who work in the hospital or who get illness. There are many medicines and these bring benefit for our lives.it is usually used for diseases treatment . Medicine is divided into two kinds : medicine for health purposes and drugs.
           Paracetamol, amoxylin, antacida, are included medicine for health purpose. It is used for diseases treatment.Meanwhile the kinds of drugs are heroin, cannabis sativa, alcohol, amfetamin. Drugs are used for illness remover, create happy feeling, and erase burden of life. It will influence to brain’s system. Wherease brain is the important organ. How if our brain damage?
           Based on UNDCP (United Nations Drugs Control Program) about 250 million human in the world consume drugs and mostly drugs consumer are educated class and the youth. The teenagers try to do anything to make themselves get impression from their friends, one of them is by using drugs.
           NAPZA (Narcotica,Pshycotropica,and Addictive subtances) are adductive substances which bring risk to the users.The users will feel relaxed, happy, and no burden.
           Because of those  reasons above, the writer is interested in choosing this topic to discuss in this scientific writing. The writer chooses  “the impacts of drugs for brain” as her scientific writing.
1.2  The statements of the problem
1.      What is drugs ?
2.      What are the impacts of drugs for brain?
3.      How do drugs impacts  the brain system?


1.3  The objectives of the problem
1.      To know what drugs is .
2.      To know the impacts of drugs for brain.
3.      To know how the drugs impacts  to the brain system.
1.4   The significance of study
This scientific writing is expected to be useful for:
1.      Students
It will motivate indonesian students to avoid using drugs. Because they will know how danger the drug is.
2.      Society
It will give information for society about the effect of drugs for brain, so that they are aware of the danger of using drugs and also prevent young generation for using drugs.
3.      Writer
After finishing this writing, the writer can improve her english writing skill, she has more knowledge about drugs and it is give impacts on brain.











CHAPTER II
Review to The Related Literature
2.1. Definition and History of Drugs
       Medicine is subtance or mixture of materials to be used in determining of diagnosing, preventing, reducing, eliminating, curing diseases or symptoms of diseases , injury or bodily or spiritual disorders in humans or animals, including to beautify the parts of human body.
            Medicine is divided into two kinds that are medicine for health purpose and drugs.Medicine for health is usually used in hospital for to relieving pain of patients during surgery and heal diseases.
Drugs is abbreviation of narcotica, psychotropica, and addictive. Drugs is an addictive  substance that gives dangerous effects for brain.
            According to the history, narcotica was used for the first time by the sumerians as a tool of treatment. The drug is processed from the sap of subtropical plant called candu or poppy (papayer souni ferum L).
            In 1810, morphine in america began to be developed as a painkiller and then the morphine spreaded widely to all of countries in america. and it is  known more for medicine. But the high diseases and more frequent use of morphine will get addiction of morphine. Morphine contains heroin which causes addiction mentally and phisycally.
            In 1874, people started to use heroin because it is considered safe. Heroin belongs to drug that is mostly used by community,because it is just used to treatment. In 1878, England passed a law to reduce the use of heroin because its addictive reaction.
            In 1906, american followed in making laws which asked pharmacy providing clear labelling of drug for any content they produced. It was intented to determine.


2.2   The kinds of drugs
1.       Narcotics
      Based on Law No:9/1976, narcotics are natural ingredient,synthetic,and semysythetic that are used as substitution for morphine or heroin, it can cause addiction.
          Based on Law RI No:23/1997 Narcotics are substances which are made from plant semysynthetic that can eliminate consciousness, lose sense, reduce or produce pain and cause addiction.
  The kinds of narcotics:
a.       Cannabis sativa /type of marijuana
Canabis sativa, on the part of the cannabis plant, which contains a substance is a narcotic sap (of flower / young leaves). Initially,  marijuana is used as remedy for pain. But it is turned out cause harmfull effect, so it is no longer used as treatment.
             
b.      Morphine
Morphine  is obtained from the plant papaver somniferum.it is  useful for reducing pain, providing a feelings of anxienty. In the medical world , morphine is used to relieve cough illness and overcome the paint of surgery. 


c.       Coca
       Coca is a plant species used only for the dried leaves, and then processed. The result is a white powder that is odorless, called cocain. Sucked is way to use it. The effects are heart attack , kidney, stroke.
The symptoms are fulminate , depresion, jumpy.

 
d.      Heroin
Heroin is semysynthetic from opoida kind of white powder, granules, liquid and taste bitter. Step to use heroin can be done in various ways :
1.      Dragon , it sucked with lips through rolls of paper or plastic on top of the aluminium foil.
2.      Sniffing , by means of inhaled through the nostrils.
3.      Puff , by putting in tobacco cigarettes.
4.      Injection, by injecting in body.
 The symptoms are : calm, little apathy, the euphoria, reduced level of consciousness, nausea, talk lisp.


                               
2.      Psychotropics
Psychotropics comes from the word psyco, means psychology and tropic means center. Psychotropics are compounds that work on the central nerve system of brain. Based on Law paragraph 01 no 5/1997 psychotropics are natural subtances or synthetic not narcotic that is psychoactive characteristic through selective
           Influence on the central nerve system. The effects are decreasing brain activity, bad occurence, illucination.
                     The kinds of psychotropic that are often misused:
a.      Deppresant
This type can reduce or relieve the central nerve system. The users can feel asleep easily.
The type of depressants are:
1.      Barbital
It is classified as a sedative used to help making a quick sleep, dispel, anxienty, tension ,and frustation. In the medical world, barbital used as sleping pills, epilepsy.
      
2.      Valium
It is usually used to treat anxienty, panic attacks, insomnia, seizures, muscle spama alcohol withdrawal. It can also be used before certain medical procedures to reduce tension and anxienty, and in some surgical procedure to induce amnesia. Valium has characteristics, they are: anticonvulsant, sedative, sceletal muscle, amnestic.
                          
3.      Rhypnol
Rhypnol is another sedative that can be used as a date rape drug. The effect including low blood pressure dizziness, abdominal cramps, confusion and impaired memory.
           
b.      Stimulant
              The substances that work to stimulate central nerve system. The stimulant type which is known more in society is caffein. It is found in coffe or tea. The effect can make nerve system be active.
      
c.       Hallucinogen
             The substances that work directly on the central nerve system have hallucination effect. Hallucinogen gives stimulation to brain. The effects, depend on the  situation of heart and the users. For example, the user has depression before swallow it tend to feel more sad after swallowing.
3.      Addictive substances
       Addictive substances are substances that have psychoactive influence, but not narcotics and psychotropics, it is called psychoactive. Because it has addicted effect if it is used continously.The kinds of addictive substances are:
a.      Alcohol drink
             Alcohol drink is a drink content of etanol. Etanol is a psycoactive material and the users awareness will decrease. If it is consumed more, alcohol will give disorder of organic mental effect that are disorder in function of think, behavior, and feeling.
b.      Inhalation
             Inhalation and solven in the form of volatile organic compounds, found in various household goods and office. The effects are: dizzy,head spinning,mild hallucination, nausea, pulmonary function disturb of heart and liver.

2.3   Human body
2.3.1 Frame work of head (skull)
       The function for protecting an important organ in the head section, that is brain.
       Brain is the control system of all of human activities. The brain also determines the physical and psychogical health of human beings. If the brain is healthy, it can support a better quality of health. However, if the brain is in trouble, it could have a negative impact on psychological health and body.
       The brain is the most important human organ. If the brain stops working one second, so the body will die. Because it is the brain that determines how to think, feel, behave, respond to something.
       The human brain consists of brain system, limbic system, and neocortex. Neocortex is distinguishes the human brain with brain of other creatures, called human because humans have brain to think.
        Human brain is the most complicated to explain, it takes days to explain in detail about the brain. Therefore, I will explain the parts of brain.



a.      Brain stem
             The brain stem is located in the bottom of skull. In the medical language , is often called the brain stem. The function of brain stem as  respiratory control, heart rate and reaction insinct in danger.
       The brain stem will respond to any incidental events. Reflax action in an earlier proof of the brain stem function. Reflex that occurs as a result of the stimulus of the brain stem of the body related to the threat situation of feeling uncomfortable about something. The brain stem was related to instinctive animal instict in humans. This can be seen in everyday activities, such as foraging, live, have children, get protection.
  The brain stem is composed 3 parts:
1.      Mesenchepalon (mid brain) is the middle top part of the brain  connection between  brain stem and cerebellum great. Midbrain controls vision and hearing.
2.      Medula oblongata is the point of the spinal nerves of the body towards the left of the right side of the body, and vice versa. Medulla serves to control the automatic functions of the brain. Such as breathing, blood circulation, respiration, and digestion.
3.      Pons, which determines whether we are awake or asleep. Pons is a transmitter that sends the data to the center along with reticular formation of the brain.

b.      Limbic system
             Limbic system is located in the middle part of the brain.the limbic system is also often referred to the brain of mammals. The limbic system consist of hypotalmus, hippocampus and amyglada. The limbic system has functions as governing emotion helps maintain hormonal balance, thirst, hunger, sexual, drive, the center pleasure, metabolism, and other long-term memory part. The limbic system has a vital role in forwarding the information received into the system memory in humans. System memory is closely associated with the ability of emotional brain.
       In the limbic system, components of hypotalamus is considered the most important element of the human brain. The hypotalamus is located in the middle of the human brain. The hypotalamus is crux of emotional strength. Function of hypotalamus is regulating hormones, desire, sexual, emotion, eating, drinking, and oraginizing pituitari gland.
c.       Neocortex
             Neocortex or often called brain thinking is part of outer layers of human brain. Function neocortex is control everything. Neocortex is also known as a center of human intellegence which is not owned by any other creature.
            Neocortex also allows to control the reptile brain and emotion (limbic system). Neocortex serves motivation, morale and give impression of a lack intimidatio or other malicious process.         
2.3.2        Order agencies
       The bones of the neck, serves to prop up the head and protect the breathing and vocal (sounds producer).
        Strenum and ribs, serves to protect the organs in the chest, like the heart (blood-pumping) and lung (breathing).
        Backbone, serves to protect the spinal cord (containing nerve cells), and serves as a member of the sustainer of the upper body. the pelvic bones serve as a connector between the upper body and lower body and as a buffer the abdomen internal organs (intensine and colon).
2.3.3   Members motion
The bones of the arm bone is made up of base the arm, radius, ulna, bones of the wrist, palm ,and bones of the fingers of the hand. Limb bones consist of femur, bone shell knees, shins, bone calves, ankle bones, the bones of the soles of the feet, and the bones of the toes.















CHAPTER III
METHODS OF WRITING
 In making this scientific writing, the writer had to use same methods and technique which consist of many steps, as follow:
3.1 Appointment of Theme
This scientific writing has theme related to the science. This theme is determined by the school. However, the writer tries to develop the theme on this scientific writing.
3.2 Appointment of Title
After studying the theme determining the school and try to develope it, the writer chose the title of this scientific writing is ” The  Effect of  Drugs for Brain“. The writer makes this title based on the background in the previous chapter.
3.3 Collection of Data
This scientific writing entitled ” The Effect of Drugs for Brain’’. The writer uses method of library research. The writer has read some books which are related to the title and also looked for some sources through internet, then made resumes of important things from the sources which can be used to make the scientific writing.
3.4 Formation of Scientific Writing
From the source which had been gotten by the writer. Further more, the writer starts to make her scientific writing while discussing with the advisor until finishing this scientific writing.The writer absolutely hopes that this scientific writing can be useful for everyone especially her self.


CHAPTER IV
DISCUSSION
4.1 kinds of drugs that impacts to the nerve system
Drug is a substance that forms a solid or a liquid or gas that causes physical changes in the occurrence and influence on the body. Almost all drugs have an effect on the central nervous system. The drugs react to the brain and can affect a person's mind feelings or behavior, this is called a drug psycoactive.
Drugs can come from a variety of sources. Many of the plants, for example the extraction of nicotine in tobacco, coffee and cocaine from cafein and from coca plants. Morphine and codeine obtained from opium crops, while heroin is made from morphine and codeine. Marijuana comes from the leaves, stalks or seeds of plants kanabis (canabis sativum) which  has oil and derived from the resin of the plant, as well as marijuana.
Alcohol is a product derived from natural ingredients are also processed through the mechanism of fermentation, it occurs when fruit, grains or vegetables made compost. Fungi such as mushroom and several types of Cactus plants are processed into drugs that are halusinogenic.
There are four kinds of drugs that affect the nervous system, namely:
1.      Sedative
Sedative  is a drug that can lead to a decrease in the normal activity of the brain. It gives effect in center nervous system and less functional activity of body, so that the wearer feel asleep easily . For example, valium.
2.      Stimulant
Stimulant is drug that can accelerate the brain works, which can result body organ like increasing brain and heart movement, from generally.So the consumer is more energetic and also tend to be happy all the time without reason . For example, cocaine.



3.      Hallucinogen
Hallucinogen is drug that lead to the onset of imagine for the wearer. The substances that work directly on the central nerve system have hallucination effect. For example, marijuana, ecstasy, and sabu-sabu.
4.      Painkiller
Painkiller is drug that hit the part of the brain which  responsible for pain. Useful for reducing pain, providing a feelings of anxienty. For example, morphine and heroin.
The use of these drugs have an impact on the working of the nervous system, such as loss of coordination of the body, because the body of the wearer, dopamine deficiency. Dopamine is a neurotransmitter found in the brain and was instrumental in the connecting on nerve impulses to other nerve cells. This causes dopamine is not generated. When nerve impulses to the head at the synapses, the bubble-bubble synapses will approach the membrane presinapsis.
However, because dopamine is not generated, the neurotransmitters cannot release their contents into the synaptic cleft so that nerve impulses are carried across to the membrane can not post synapses. The condition causes no occurrence of the post synaptic depolarisation membrane  potential work does not occur because the nerve impulses cannot propagate to the next nerve cell.
Another effect of the use of illegal drugs is the loss of control of motion (the user will overacting, like spirit to work , muscle awareness (the muscle is tense because the drugs entered into blood circulation), weakened heart rate ( the tick of heart will work abnormally,so damage the tool respiration), going on stomach cramps so it cause diarrhea,and even result in death.

The dangerous drugs that are included in a group of drugs that affect the central nervous system (CNS/CNS) is a drug that can be addictive (drug addict). According to the general classification of drugs that affect the CNS many types exist that are addictive and non-addictive.
Division of medicinal drugs that affected the central nervous system:
1.Depresansia CNS Drugs
Drugs including the arthritis drug is inhibiting activity of CNS specifically nor the public. Which include inhibiting the CNS in General is a general anaesthetic in a group of drugs, in this chapter that is not discussed. they  are:
a. sedative drugs
Included in this category is drugs that cause mild depression (sedative) effects happen to sleep (hipnotica). On the effects of sedative sufferers will be quieter because of the sensitivity of cortex serebrum decreases. In addition to environmental awareness, motor activity and decreased spontaneous reactions.
The condition clinically symptoms indicate sluggishness and drowsiness. The drug's sedative-hypnotic is Ethanol (alcohol).
b. the analgesic
The drugs is analgesic is a drug that arthritis pain omission (opioid analgesic) drug and anti piretic anti inflammatory drugs as well as the non-steroids. as discussed in this chapter are the opioid analgesic drugs because these drugs may give rise to addictive group, for example: Morphine, Pentazocine, Naloxone Codein, Etc.


2. Drug stimulansia SSP
Drug stimulansia works on the nervous system by increasing the transmission to or left brain. The stimulant can cause people increase the heart rate, body temperature and blood pressure. Other physical effects is lower the appetite, pupil dilation, talkative, agitation and sleep disorders. When granting excessive stimulant can cause anxiety, panic, headaches, stomach spasms, aggressive and paranoid.
3. Halusinogenic Drug
Halusinogenic effect on the perception of the drug for its users. People who consume such drugs will be the person who often hallucinate, for example they hear or feel something that turned out not to exist. The influence of the drug halusinogenic is highly variable, making it difficult to forecast how or when they begin to hallucinate.
The influence of the drug halusinogenic is pupil dilation, increased activity ( the people will overacting), a lot of talking or laughing, emosional, psycologic, sweating,panic, euphoria, paranoid, loss of awareness of reality, irational, stomach cramps and nausea.
4.2  How drugs work and impacts the brain
           
The drug gets into the body, by way of ingested, inhaled, or injected, then drugs alter the biochemistry of the neurotransmitter on the system arrangement of the limbus. Because there is drug intake from the outside, the production in the body has stopped or interrupted, so he will always need drugs from outside.
Drugs effect on the part of the brain responsible for feelings of life. like Changes in mood (calming, relaxed, happy, and taste-free), Changes in the mind (stress disappear and increasing imagination), Changes in behavior (increasing familiarity, inhibits value, and out of control).and then drugs will enter into the limbus system: Hypothalamus ( the pleasure Centre in the brain ) is part of the limbus. The drug produces a feeling of ' high ' by changing the biochemical makeup of the molecules in the brain cells.
In brain cells there is an assortment of chemicals called neurotransmitters. A chemical works on the nerve cells of one connection with other nerve cells (Synapse). Some of the neurotransmitter that is similar to some types of drugs. All psychoactive substances (narcotics, psychotropic drugs and other addictive substances) can change behaviors, feelings and thoughts of a person through its effects on more neurotransmitters.
It happened on a dependency is a kind of brain cells learning at the center of pleasure. If consuming drugs, brain read that person's response. If the people feel comfortable, the brain secretes the neurotransmitter and will give the impression of pleasant. If using drugs again, people come back to feel as though her inner needs favors sated. The brain will record it as something to be sought as a priority for fun. As a result, the brain makes the program is wrong, as if the people that need it as a basic requirement. Case addiction or dependence.
In spite of the bad impact, drug users will feel there's a mood changing. All types of drugs change the way of thinking and feeling of a person depends on the type.For users of narcotic drugs, may not be realized if result do drugs will destroy the workings of her brain. Drug usage greatly affect the working of the brain that serves as the control center of the body and affect all body functions. Because it works on the brain, drugs alter mood of feeling, thinking, consciousness and behavior of the wearer. That is why the drug is called psychoactive substances.
On dependence, one should always do drugs, if not, the symptoms are substance arise, if its use is stopped or reduced in number. The symptoms depend on the type of drug used. Symptoms of a broken opioida (heroin) is similar to the pain of heavy flu, runny, is out of tears, body hair stand, muscle aches, nausea, vomiting, diarrhea, and sleeplessness.




interaction with brain
drugs consumed by the people
drugs entered into blood circulation
                                                                                                                        
 



WORK OF DRUGS EFFECT TO THE BRAIN
entered into lymbus  system ;hypotalamus
neutrotransmitter chemical substances
chemical substances give massage to the brain
 






brain make the wrong program
                                                                       
 

                                                                                         


4.3  What to do to addictive people.
1.      Perform preventive manner (prevention), which is to form a community that has durability and resistance to drugs. Prevention is better than eradication. Drug abuse prevention can be done in various ways, such as coaching and counseling and supervision in the family, counseling by a competent person both in school and society, recitation by scholars, monitoring places of entertainment night by security forces, control the distribution of illegal drugs and perform other actions that aim to reduce or eliminate the chance of occurrence of drug abuse.
2.       Repressive (enforcement), that is cracked and combating drug abuse through law and under the law, which is conducted by law enforcement or security forces assisted by the community. If people know it should be immediately reported to the authorities (police) and should not be vigilante.
3.       approach through curative (treatment), aimed at healing the victims either medically or with other media. In Indonesia has many established places of healing and rehabilitation of drug addicts as grebes Respati Foundation, boarding schools, foundations cottage Bina Love etc.
4.       rehabilitation (rehab), do so after treatment of the victims do not recur "addictive" drugs. Rehabilitation seeks to sympathize and appropriately treat the victims of drugs in order to get back into society in a state of physical and spiritual health. We must not alienate the victims were already aware Drugs and repent, so they do not fall back as a drug addict.














                                             






CHAPTER V
CLOSING

5.1  Conclusion
Based on the result from this scientific writing, the writer has a conclusion that is:
1.      Drug is a substance that forms a solid or a liquid or gas that causes physical changes in the occurrence and influence on the body. Drugs are  divided into three kinds, that is narcotica, psycotropyca, and addictive subtances.
2.       The most dangerous is psychotropic, because psychoactive has natural effects for brain and behavior that can cause changes in mental activity and behavior for the users. example: barbital, valium.
3.      Almost all drugs have an effect on the central nervous system, because the neurotransmitter in the brain is connecting on nerve impluses to other nerve cells.  The drugs reacted to the brain and can affect a person's mind feelings,     behavior, lost of coordination of body and it makes addictive.
5.2  Suggestion
After knowing about all of the discussion above, the writer hopefully will give the suggestion which has purpose to keep everybody to stay away from drugs. don’t approach the user and don’t try to consume drugs. Because try once, the people will consume again and always be  closer  to the God.





BIBLIOGRAPHY

Aryulina,Diah.dkk.2004.Biologi 2 SMA dan MA untuk kelas XI.Jakarta:Esis.
Musami,Teguh.2011.Otak Sehat Ingatan Dahsyat.Yogyakarta.Buku Pintar.
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